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 Nutritional Medicine: Treatments Currently Used for Cancer 
 
In order to know where we are going in cancer treatment, it is important to know where we have been and how we got where we are. This chapter looks at both conventional and alternative cancer treatment methods to give you a better understanding of our "roots" in cancer treatment options. For a more thorough discussion of conventional therapies, read CANCER THERAPY by Mallin Dollinger, MD; for alternative therapies, read CANCER THERAPY by Ralph Moss, PhD.

Conventional Therapies

Chemotherapy is a spin-off product from the chemical warfare of World Wars I and II and is now given to 75% of all American cancer patients. Yale University pharmacologists who were working on a government project during World War II to develop an antidote for mustard gas noted that bone marrow and lymphoid tissue were heavily damaged by these poisons. That observation led to experiments in which mustard gas was injected into mice with lymphomas (cancer of the lymph glands) and produced remission. In 1943, researchers found that mustard gas had a similar effect on human Hodgkins disease.1 Chemo has also become a useful agent against testicular cancer, which is now 92% curable. Most proponents of chemo now recognize the limitations of using chemo as sole therapy against many types of cancer.

Shortly after these initial exciting discoveries, progress on chemo cures quickly plateaued and forced the innovative thinkers into creative combinations of various chemo drugs, which is now the accepted practice. In the 1980s, oncologists began using chemo by "fractionated drip infusion" in the hospital rather than one large (bolus) injection in the doctor's office. The fractionated method was not only more effective against the cancer but also less toxic on the patient. Think of the difference in toxicity between taking 2 glasses of wine with dinner each night, or guzzling all 14 glasses at one time at the end of the week. Also, fractionated drip infusion is more likely to catch the cancer cells in their growth phase, while bolus injections are a random guess to coincide with the growth phase of cancer. In the next evolutionary step, borrowing from technology developed for heart disease, oncologists began using catheters (thin tubes) that could be inserted into an artery (called intra-arterial infusion) to deliver chemo at the site of the tumor, once again improving response and reducing overall toxicity.

Radiation therapy is given to about 60% of all cancer patients. In 1896, a French physicist, Marie Curie discovered radium, a radioactive metal. For her brilliance, Madam Curie was eventually awarded two Nobel prizes and was considered one of the founders of radiation therapy and the nuclear age. For her unprotected use of radioactive materials, she eventually died while still young of leukemia. Cancer patients were soon being treated with a new technique developed by the German physicist, Wilhelm Roentgen, called radiation therapy. This technique relies on regional destruction of unwanted tissue through ionizing radiation that disrupts the DNA of all bombarded cells. Radiation therapy can be externally or internally originated, high or low dose and delivered with uncanny computer-assisted precision to the site of the tumor. Brachytherapy, or interstitial radiation therapy, places the source of radiation directly into the tumor, as an implanted seed. New techniques use radiation in combination with heat therapy (hyperthermia).

Surgery is the first treatment of choice for about 67% of cancer patients. By 1600 B.C., Egyptian physicians were excising tumors using knives or red-hot irons.2 By physically removing the obvious tumor, physicians feel that they have the best chance for overall success. Unfortunately, many tumors are so entwined with delicate body organs, such as brain and liver, that the tumor cannot be resected (cut out). Another concern is that partial removal of a cancer mass may open the once-encapsulated tumor to spread, like opening a sack of dandelion seeds on your lawn.

Biological therapies, as with most other discoveries, were the product of accidents being observed by a bright mind. William B. Coley, MD, a New York cancer surgeon scoured the hospital records around 1890 looking for some clue why only a minority of patients survived cancer surgery. He found that a high percentage of survivors had developed an infection shortly after the surgery to remove the cancer. This observation led Dr. Coley to inject a wide variety of bacteria, known as Coley's cocktail, into his cancer patients, who then underwent the feverish recovery phase, with noteworthy cancer cures produced. Infections were found to induce the immune system into a higher state of activity, which then helped to destroy tumors. From this crude beginning, molecular biologists have found brilliant ways of producing injectable amounts of the immune factors that can theoretically fight cancer.

Even amidst our polluted, overstressed and poorly nourished society, most people do not die of cancer--due to the protection afforded by our immune systems; which is a well-orchestrated army of specialized cells that kill invaders, like cancer, bacteria and viruses. An over-reactive and out of balance immune system creates auto-immune diseases, such as allergies, asthma, Crohn's disease and arthritis. An under-reactive immune system leaves the person open to cancer, infections and premature aging.

Biological therapies attempt to fine tune and focus the immune system into a more vigorous attack on the cancer. Lymphokines are basically "bullets" produced by the immune system to kill invading cells, such as cancer. Lymphokine activated killer cells (LAK) are incubated in the laboratory in the presence of a stimulator (interleukin-2) and then injected back into the cancer patient's body for an improved immune response.3 In some lab tests, LAK cells swarm on the tumor like ants on honey.

Interferon, interleukin, monoclonal antibodies and tumor necrosis factor are among the leading contenders as biological therapies against cancer. The downside of biological therapies is that most forms have extremely toxic side effects, and none can be legally used even in approved experiments unless that patient has been considered untreatable by the other three conventional means. The National Cancer Institute is beginning to place more emphasis on researching biological therapies.

Heat Therapy (hyperthermia). Cancer cells seem to be more vulnerable to heat than normal healthy cells. Since the time of Hippocrates and the Egyptian Pharoahs, heat therapy has been valued. Experts have shown that applying heat to the patient elevates immune responses. Temperatures of 42 degrees Celsius or 107 degrees Fahrenheit will kill most cancer cells, but can be quite stressful on the patient also. Could it be that exercise induces regular "hyperthermia" to kill off cancer cells before they can become a problem?

Whole body hyperthermia involves a very sophisticated hot tub device, general anesthesia and medical supervision. Regional hyperthermia can involve either a miniature waterbed-like device applied to the tumor or focused microwaves. Major cancer research centers, including Stanford and Duke, have found this therapy useful by itself, or used synergistically to improve the response to chemo and radiation therapy.

Alternative Therapies

If you need emergency medical care, reconstructive surgery, orthopedic surgery or critical life support, then an American hospital is where you will get the world's best care. That's why alternative emergency care does not exist, because our current system is working just find, thank you very much. Unfortunately, not all areas of American medicine have such an impressive track record of success. Many patients with cancer, Chronic Fatigue Syndrome, arthritis, AIDS, multiple sclerosis, Alzheimer's, mental illness and muscular dystrophy find little help from traditional medicine. When the accepted approach does not work, the grounds are fertile for "alternative" approaches to develop.

Among the many advantages of living in America, we are blessed with abundant individual liberties as guaranteed by the Constitution and Bill of Rights. And we fight viciously to preserve these rights. The controversy of alternative cancer treatment basically centers around the question "Which is more important: the patient's right to choose whatever health care they want, or the responsibility of the government to protect the unwarey consumer from fraudulent practices?" This question is heated, polarized and regularly doused with the emotional testimonies of someone who was cured through alternative therapy after conventional therapy told he or she to "go home and get your affairs in order."

Studies now show that up to 50% of all cancer patients use some form of unconventional cancer therapy, with most of these people being of above-average income and education.4 A newer study reported in the New England Journal of Medicine from David Eisenberg, MD of Harvard Medical School shows that Americans make more visits to alternative therapists than to family physicians. Since the patient usually pays for alternative therapists while insurance pays for most expenses in a family physician visit, these numbers are quite astonishing. People don't keep going back and paying out of pocket expenses unless they are getting some relief for their health problem. This information somewhat debunks the theory that the government is protecting poor uneducated minority consumers from predatory, dangerous and unproven health care specialists.

While critics brand alternative cancer therapies as "unproven, questionable, dubious, quackery and fraudulent"; proponents prefer the labels "complementary, comprehensive, innovative, nontoxic, holistic, natural and noninvasive." Meanwhile, the American Cancer Society has kept a list of about 100 cancer therapies that the ACS calls "unproven". This blacklist has become the "gatekeeper" in cancer treatment in America. Insurance companies will not reimburse for "unproven or experimental" therapies.

Yet, are we using dual standards in judging our health care options? According to the Office of Technology Assessment, only 10-20% of all surgical procedures practiced in the United States have been "proven" to be effective by controlled clinical trials.5 Much of what Americans do throughout medicine, law, education and even business are more based on a "Grandfather clause" or tradition, rather than being the best way to do things. We oftentimes "pave cow paths" which are usually inefficient routes from point A to point B, then consider these sacred and inviolable. If 50% of cancer patients this year will seek alternative cancer care, which is non-reimburseable, imagine the stampede toward alternative cancer treatment if people could choose their own therapies.

Improvement in cancer treatment options may be coming soon. Retired Iowa Congressman Berkley Bedell could only find cures for his Lyme disease, then advanced and untreatable prostate cancer from alternative therapists. Mr. Bedell told his powerbroker friends on Capitol Hill of his experiences. Senator Tom Harkin, chairman of the subcommittee on health issues, then convinced his colleagues to allocate $2 million to form the Office of Alternative Medicine as a branch of the National Institutes of Health. Many insurance companies are awakening to the profitability of alternative cancer therapy because: 1. the public wants it and is willing to pay for it, 2. alternative cancer therapy costs about 10% of conventional cancer care and therefore can be more profitable. Some pioneering insurance companies now reimburse for alternative cancer treatment.6

The medical freedom advocates argue that a person afflicted with a terminal disease deserves a chance at whatever therapies offer hope. Meanwhile, the Food and Drug Administration cites examples in which premature permission to use newly discovered therapies ended in disaster--like the Thalidomide situation. However, lets compare the risk to benefit ratio of Thalidomide and alternative cancer treatment:

It is unconstitutional to think that protecting the end-stage and otherwise untreatable cancer patient from inexpensive and non-toxic therapies is a government obligation. AIDS patients have become models of political activism and have won this logic debate as the Food and Drug Administration now allows many "compassionate use" variances for otherwise unapproved drugs in AIDS therapy. Cancer patients, also, need a broader scope of treatment options. To quote Hippocrates, the father of modern medicine, 2400 years ago: "Extreme diseases call for extreme measures." Nutrition therapy, surely, is no more extreme than chemo, radiation therapy or surgery.

Alternative cancer therapies would best be categorized as:

It is clear that humans are a complex interplay of physical and metaphysical forces. Many documented cases of paranormal psychology have shown that people can alter autonomic bodily functions by entering suspended animation, walking on hot coals without any burns, reading minds and living outside the laws of nutrition. As humans become more spiritual or metaphysical, we tend to transcend physical laws. Hence, the ultimate cancer cure may come from this relatively untapped area of healing.
(Excerpted from Beating Cancer with Nutrition: Clinically Proven and Easy-To-Follow Strategies to Dramatically Improve Quality and Quantity of L ISBN: 0963837281)
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 About The Author
Patrick Quillin PhD, RDDr. Patrick Quillin, an internationally respected expert in the area of nutrition and cancer, has served as the Director of Nutrition for Cancer Treatment Centers of America (800-577-1255) for the past ten years.......more
 
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